BIOLOGY 09.356: Schedule, Spring 1999


Week Lecture Topics Text Problems Lab

1/191/19: INTRODUCTION, HISTORICAL OVERVIEW
1/20: REVIEW OF MENDELIAN INHERITANCE
1/22: EXTENSIONS OF MENDELIAN INHERITANCE
KC: 1
KC: 3
KC: 4
KC: 1:3,5,6,10,11 3:1,2,6,9,17, 22,26, 28,32,35,36
W:1,2
Lab 1. Dihybrid crosses
1/261/26: EXTENSIONS OF MENDELIAN. (cont.)
1/27: problem tutorial*: mono and dihybrids, X2
1/29: MITOSIS, MEIOSIS, CHROMOSOMAL THEORY OF INHERITANCE
2. Predator/prey results due Jan 29th
KC: 4

KC: 2

KC:4: 2,3,4,8,10 17,19,2027,3 2,3738, 39; KC: 2:1,3,4,6,18, 28
W: 3,4
Lab 1. (count plants, F2);
Lab 2. Predator /prey Analysis
2/022/2: LINKAGE AND RECOMBINATION
2/3: problem tutorial: epistasis, multi-gene
2/5: LINKAGE MAPPING
Portfolio: KC: 3:38,39;4:45,47 due Feb 5th
1. Dihybrid lab REPORT due Feb. 8th
KC: 5

KC: 7

KC: 5:2,4,10,18,2 0, 24,27; 7:6,7,14,10
W: 5,6;
Lab 3. 3-point fly crosses
2/092/9: SEX DETERMINATION and LINKAGE
2/10: problem tutorial*:linkage and mapping
2/12: PEDIGREES
Portfolio: KC:5:29; 7:17; 8:15; 9:43 due 2/15
KC: 8,9 (to 234)
CK:8: 1,2,3,9,11
9: 1,3,6,11,28, 32, 36,37; W: 7,8
Lab 3. (discard parents); Lab 4. Restriction mapping
2/162/16: EXAM 1 (CHAPTERS 1-9)
2/17: problem tutorial*: STRUCTURE OF DNA
2/19:ORGANIZATION OF GENETIC INFORMATION
KC: 9 (end), 10,11 KC: 10:8,10,14,17,18,26; 11:1,21,22,25
W: 10, 12
Fong research
Lab 3. (count flies, F1)
Lab 4.
(gels)
2/232/23DECIPHERING THE GENETIC CODE
2/24: problem tutorial*
2/26:TRANSCRIPTION & TRANSLATION
4. Restriction mapping results due Feb 26th
KC: 12,13KC: 12:3,6,7,13,31; 13:6,12,17.20,24
W
: 11
Kirby research
Lab 3. (discard parents)
Lab 5.
DNA sequencing
3/023/2:GENETIC MUTATIONS & DNA REPAIR
3/3: problem tutorial
3/5:GENETIC MUTATIONS and DNA REPAIR cont
Portfolio: KC: 10:29,11:25, 12:33
KC: 14-16KC: 14: 3,5,6,11,13,14,17,18, 30
Lab 3. (count flies, F2)
3/093/9:RECOMBINANT DNA TECHNIQUES
3/10: problem tutorial*
3/12:RECOMBINANT DNA TECHNIQUES cont.
3. Drosophila lab REPORT due Mar. 25th
KC: 15,16
KC:15:7,8,9,11,17,21;16:2,4,6,10,11
Lab 6. Sequence computer lab
3/233/23:GENOMIC ORGANIZATION OF DNA
3/24: problem tutorial*
3/26: POPULATION GENETICS
KC: 17
KC: 24
KC: 17:1,6,7,10,12,13; 24: 1,6,11,14,17,20,21.

Schaeff research
Lab 7. DNA fingerprint lab
3/303/29:EXAM 2 (CHAPTERS 9-16)
3/30:problem tutorial*
4/01:REGULATION OF GENE EXPRESSION
6. Sequence results due Apr 5th
7. DNA fingerprint results due Apr 9th
KC: 18,19KC: TBA
W: 14,15
Lab 8. Genetic engineering lab
4/064/6:REGULATION OF GENE EXPRESSION cont.
4/7:problem tutorial*
4/9:EVOLUTIONARY GENETICS
8. E. coli results due Apr 13th
KC: 25KC: TBALab 9. Natural selection experiment
4/134/13:EVOLUTIONARY GENETICS
4/14:problem tutorial*
4/16:GENETICS OF BEHAVIOR
9. Natural selection results due Apr 23rd
KC:23LAB 10. TBA
4/204/20:DEVELOPMENTAL GENETICS
4/21:problem tutorial*
4/23:DEVELOPMENTAL GENE REGULATION
Portfolio: TBA
KC: 18, 19&20 KC:< /U>;18,19&20;

Hursh research

LAB 11. Developmental genetics
4/274/27:GENETICS AND CANCER
4/28:problem tutorial*
4/30:CANCER cont.
KC: 21- 23KC: 21-23LAB 11. Developmental genetics (cont)

* Problem tutorials are not lectures. Students should have already worked on the assigned problems before coming to class.

NOTE: The final exam is cumulative with particular emphasis on the material covered in the latter third of the course.